- Ambassador: Denise Bauer
- Deputy Chief of Mission: Brian Aggeler
- Minister Counselor for Consular Affairs/Consul General: Colombia Barrosse
- Minister Counselor for Economic-Environment, Science, Technology and Health Affairs: Amy Schedlbauer
- Minister Counselor for Management: Keith Heffern
- Minister Counselor for Public Affairs: Mark Toner
- Minister Counselor for Political Affairs: Liam Wasley
- Regional Security Officer: Tanya Sears
- Director Africa Regional Services: Brenda Soya
- Consulate General Marseille: Kristen K. Grauer
- Consulate General Strasbourg: Darragh Paradisio
- APP Bordeaux: Alexander Lipscomb
- APP Lyon: Christopher Crawford
- APP Rennes: Elizabeth Webster
- Minister Counselor for International Development: Christophe Tocco
- Attaché/Special Agent in Charge, Air Force Office of Special Investigations (AFOSI): pending
- Chief Operating Officer, American Battle Monuments Commission (ABMC): John Wessels
- Counselor for Agricultural Affairs: David Leishman
- Director – USDA-ARS European Biological Control Laboratory: Michael Grodowitz
- Defense Attaché: Colonel Allen Pepper
- Marine Security Guard Detachment Commander: SSGT Jacob Green
- Chief, Office of Defense Cooperation France: Colonel Michael McCullough
- Department of Energy Attaché: Erika Hunsicker
- Department of Justice (DOJ) Attaché: Andrew Finkelman
- Department of Justice – Drug Enforcement Administration, Country Attaché: Matthew Keller
- Department of Homeland Security Attaché: Sonny Kilmer
- Federal Aviation Administration Representative: Jennifer Solomon, Attachée
- Federal Bureau of Investigation – Legal Attaché: Jarrad Smith
- Minister Counselor for Commercial Affairs: Scott Pozil
- NASA European Representative, Space Attaché: Matthew Koeppe
- Naval Criminal Investigative Service (NCIS) Senior Attaché: Davin Pascale
- Secret Service, Special Agent in Charge (SAIC): Jocelyn Keaveney
- Transportation Security Administration (TSA) Representative / Attaché: Michael Donnelly
U.S. Mission to O.E.C.D: Chargé d’Affaires Whitney Baird